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Traditional Chinese medicine compound for treating rheumatoid arthritis and preparation method of patch thereof

A technology for rheumatoid and arthritis, which is applied in drug combinations, anti-inflammatory agents, pharmaceutical formulas, etc., can solve the problems of toxic and side effects of chemical drugs and high prices, and achieve a good clinical promotion effect

Inactive Publication Date: 2019-04-05
DALIAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the problem of toxic and side effects and relatively high price of chemical drugs for treating rheumatoid arthritis, the invention provides a preparation method of a traditional Chinese medicine composition for treating rheumatoid arthritis and a patch thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A traditional Chinese medicine composition patch for treating rheumatoid arthritis, the parts by weight of the raw materials of the traditional Chinese medicine composition are: 20 parts of broadleaf nettle, 15 parts of turmeric, 15 parts of green vine, 10 parts of chuanxiong, 3 parts of papaya, 3 parts of white peony root and 3 parts of Nepeta mustard. The preparation steps are:

[0024] (1) Weigh 20 parts of broadleaf nettle, 15 parts of turmeric, 15 parts of green vine, 10 parts of chuanxiong, 3 parts of papaya, 3 parts of white peony, and 3 parts of Nepeta, crushed and extracted with 95% ethanol under reflux for 2 hours , the ratio of solid to liquid is 1g: 4ml, the temperature is 80 ° C, the extract is filtered, and concentrated to obtain the extract.

[0025] (2) The above-mentioned medicinal extract is injected into the depression of the compressed cotton anti-seepage ring, heated and dried until the relative density of the extract is 1.05, and the pressure-sens...

Embodiment 2

[0027] A traditional Chinese medicine composition patch for treating rheumatoid arthritis, the parts by weight of the raw materials of the traditional Chinese medicine composition are: 30 parts of broadleaf nettle, 20 parts of turmeric, 20 parts of green vine, 15 parts of chuanxiong, 6 parts of papaya, 6 parts of white peony and 6 parts of Nepeta. The preparation steps are:

[0028] (1) Weigh 30 parts of Nettle broadleaf, 20 parts of turmeric, 20 parts of Cypress vine, 15 parts of Chuanxiong, 6 parts of papaya, 6 parts of Paeonia lactiflora, 6 parts of Nepeta, crushed and extracted with 95% ethanol under reflux for 2 hours , the ratio of solid to liquid is 1g: 4ml, the temperature is 80 ° C, the extract is filtered, and concentrated to obtain the extract.

[0029] (2) The above-mentioned medicinal extract is injected into the depression of the compressed cotton anti-seepage ring, heated and dried until the relative density of the extract is 1.05, and the pressure-sensitive ad...

Embodiment 3

[0031] A traditional Chinese medicine composition patch for treating rheumatoid arthritis, the parts by weight of the raw materials of the traditional Chinese medicine composition are: 35 parts of broadleaf nettle, 30 parts of turmeric, 25 parts of green vine, 25 parts of chuanxiong, 10 parts of papaya, 10 parts of Paeonia lactiflora, 10 parts of Nepeta, the preparation steps are:

[0032] (1) Weigh 35 parts of Nettle broadleaf, 30 parts of turmeric, 25 parts of Cinnamon vulgaris, 25 parts of Chuanxiong, 10 parts of papaya, 10 parts of Paeonia lactiflora, 10 parts of Nepeta, crushed, and extracted with 95% ethanol under reflux for 2 hours , the ratio of solid to liquid is 1g: 4ml, the temperature is 80 ° C, the extract is filtered, and concentrated to obtain the extract.

[0033] (2) The above-mentioned medicinal extract is injected into the depression of the compressed cotton anti-seepage ring, heated and dried until the relative density of the extract is 1.05, and the pressu...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine compound for treating rheumatoid arthritis and a preparation method of a patch thereof. The traditional Chinese medicine compound is prepared from the following raw materials in parts by weight: 20-35 parts of urtica laetevirens, 15-30 parts of radix curcuma, 12-25 parts of caulis sinomenii, 10-25 parts of rhizoma chuanxiong, 3-10 parts of fructus chaenomelis lagenariae, 3-10 parts of radix paeoniae alba and 3-10 parts of herba schizonepetae. The preparation method of the patch comprises the steps that according to the requirements of weight parts of the traditional Chinese medicine compound, raw materials of the urtica laetevirens, the radix curcuma, the caulis sinomenii, the rhizoma chuanxiong, the fructus chaenomelis lagenariae, the radix paeoniae alba, the herba schizonepetae and the like are weighed, and are crushed, 95% ethyl alcohol is used for heating reflux extraction for 2 h, a solid-liquid ratio is 1 g to 4 ml, temperature is 80 DEG C, extraction liquid is filtered, and concentration is conducted to obtain extract; 2, the medicine extract is injected into a medicine storage layer, the medicine storage layer is heated and dried until the relative density of the extract is 1.05, and a pressure-sensitive adhesive layer, the medicine storage layer and a protective layer are sequentially stuck together, so that the patch is obtained. The patch is a safe and effective medicine for treating and preventing rheumatoid arthritis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method of a patch. Background technique [0002] Rheumatoid arthritis is a chronic, progressive, and aggressive autoimmune disease with progressive and recurrent episodes. Rheumatoid arthritis occurs nationwide, with a prevalence of 0.3-0.4% in my country. The clinical manifestations of rheumatoid arthritis include pain, joint swelling and functional decline. At present, glucocorticoids, non-steroidal anti-inflammatory drugs and biological preparations are mainly used in clinical treatment of rheumatoid arthritis. The price is moderate and has great advantages, so it is necessary to develop anti-rheumatoid arthritis drugs with less toxic and side effects starting from traditional Chinese medicine resources. SUMMARY OF THE INVENTION [0003] Aiming at the problems of toxic and side effects and relatively high price of chemical drug...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P19/02A61P29/00
CPCA61K36/185A61K36/236A61K36/538A61K36/59A61K36/65A61K36/71A61K36/732A61K36/9066A61K2236/333A61P19/02A61P29/00A61K2300/00
Inventor 史丽颖王柳于大永
Owner DALIAN UNIVERSITY
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