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A pharmaceutical composition for reducing blood uric acid level and preparation method thereof

A technology of composition and blood uric acid, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve hyperuricemia, gout, affecting treatment development, and severe gastrointestinal reactions that cannot be cured To achieve the effect of no toxic side effects, good clinical cure rate, and improvement of clinical symptoms

Active Publication Date: 2020-11-06
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The pathogenesis of gout and hyperuricemia has not yet been fully clarified. In terms of treatment, Western medicine currently only stops at using drugs to improve symptoms and control uric acid levels, such as colchicine, non-steroidal anti-inflammatory drugs, glucocorticoids and other drugs , have not yet been able to cure hyperuricemia and gout, and are likely to cause severe gastrointestinal reactions and other adverse events, which will affect the development of treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation of embodiment 1 composition of the present invention

[0027] Prescription: Guizhi 20g, Turmeric 20g, Fangji 20g, Plantago Seed 20g, Arrowhead Mushroom 10g, Evodia 15g.

[0028] Preparation Process:

[0029] (1) Weigh each bulk drug according to the prescription;

[0030] (2) The first step: first put the medicinal materials into the casserole, add 2000ml of water, and soak for half an hour. Step 2: After boiling with strong fire (high fire), boil with slow fire (low fire) until 300ml is left, and pour the boiled medicinal liquid into a bowl. Step 3: Repeat Step 1 (without soaking) and Step 2, and take it twice before and after.

Embodiment 2

[0031] The preparation of embodiment 2 compositions of the present invention

[0032] Prescription: Guizhi 17g, Turmeric 17g, Fangji 23g, Plantago 23g, Arrowhead Mushroom 13g, Evodia 18g.

[0033] Preparation process: with the preparation process of embodiment 1.

Embodiment 3

[0034] The preparation of embodiment 3 compositions of the present invention

[0035] Prescription: Guizhi 23g, Turmeric 23g, Fangji 17g, Plantago 17g, Arrowhead Mushroom 7g, Evodia 12g.

[0036] Preparation process: with the preparation process of embodiment 1.

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Abstract

The invention provides pharmaceutical composition for reducing blood uric acid level. The pharmaceutical composition is prepared from the following bulk drugs by weight: 17-23 parts of ramulus cinnamomi, 17-23 parts of rhizoma curcumae longae, 17-23 parts of radix stephaniae tetrandrae, 17-23 parts of semen plantaginis, 7-13 parts of appendiculate cremastra pseudobulb and 12-18 parts of fructus evodiae. The invention further provides a preparation method and an application of the composition. The composition is reasonable in compatibility, has obvious effect on reducing the blood uric acid level and can be used for treating hyperuricemia and gouty arthritis, and a novel drug is provided clinically.

Description

technical field [0001] The invention relates to a pharmaceutical composition for reducing blood uric acid level, its preparation method and application. Background technique [0002] Uric acid is the final product of purine metabolism in the body, which is mainly excreted by the kidneys. When the concentration of uric acid in the blood exceeds the normal value, the uric acid is easy to deposit in soft tissues or joints, causing acute inflammatory reactions, leading to hyperuricemia, gout, etc. . [0003] With the improvement of people's living standards and changes in dietary structure, the excessive intake of high-purine foods will cause purine metabolism to become disordered, and uric acid in the blood will increase, leading to an increasing trend in the incidence of gout and hyperuricemia worldwide. The data shows that the incidence of gout and hyperuricemia in my country has risen sharply at a rate of 7.5% per year, and the number of gout and hyperuricemia in China has ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P19/06A61P19/02
CPCA61K36/54A61K36/59A61K36/68A61K36/754A61K36/898A61K36/9066A61K2236/331A61K2236/39A61K2300/00
Inventor 高培阳张雪梅张传涛
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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