A kind of chrysanthemum salt, chrysanthemum salt toothpaste containing chrysanthemum salt and preparation method of chrysanthemum salt toothpaste

A technology of toothpaste and extract, which is applied in dentistry, pharmaceutical formulations, cosmetic preparations, etc. It can solve the problems of poor taste, poor prevention and treatment effect of salt-containing toothpaste, and achieve the effect of inhibiting and alleviating gingival inflammation

Active Publication Date: 2019-12-17
江西草珊瑚口腔护理用品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the prevention and treatment effect of salt-containing toothpaste is relatively poor, and the taste is poor

Method used

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  • A kind of chrysanthemum salt, chrysanthemum salt toothpaste containing chrysanthemum salt and preparation method of chrysanthemum salt toothpaste

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preparation example Construction

[0025] The preparation method of described wild chrysanthemum extract comprises the following steps:

[0026] 1) using ethanol aqueous solution as the extraction solvent, carrying out reflux extraction to the wild chrysanthemum, and obtaining the ethanol extract;

[0027] 2) Concentrating the ethanol extract obtained in step 1) to obtain an ethanol concentrate;

[0028] 3) Adsorbing the ethanol concentrate obtained in step 2) with a macroporous resin, and eluting with an aqueous ethanol solution to obtain an ethanol eluent;

[0029] 4) Concentrating the ethanol eluate obtained in the step 3) to obtain the extract of Chrysanthemum chrysanthemum.

[0030] In the present invention, the weight ratio of the wild chrysanthemum extract to sodium chloride is preferably 3:1-30:1, more preferably 5:1-20:1, most preferably 8:1-15:1.

[0031] In order to obtain the wild chrysanthemum extract, the present invention adopts ethanol aqueous solution as an extraction solvent, carries out ref...

Embodiment 1

[0067] 1) Mix 100 g of wild chrysanthemum with 12.5 g of 50% ethanol aqueous solution, and carry out reflux extraction at 65° C. for 2 times, each extraction for 3 hours, to obtain an ethanol extract;

[0068] 2) Concentrate the ethanol extract obtained in step 1) under a pressure of 0.08 MPa, and filter to obtain the ethanol concentrate;

[0069] 3) The ethanol concentrate obtained in step 2) is adsorbed with a macroporous resin with 5 times the weight of the ethanol concentrate, and after the adsorption is completed, it is eluted with a 60% ethanol aqueous solution with a volume fraction of 60% ethanol aqueous solution and the ethanol concentrate. Weight ratio is 10:1, obtains ethanol eluent;

[0070] 4) Concentrating the ethanol eluent obtained in step 3) under a pressure of 0.09 MPa to obtain the wild chrysanthemum extract, the specific gravity of the wild chrysanthemum extract is 1.1; the total flavonoid content is 9.3 mg / ml;

[0071] 5) Mix and dissolve the wild chrysan...

Embodiment 2

[0073] 1) After drying and crushing 100 g of wild chrysanthemum, pass through an 80-mesh sieve and mix with 10 g of ethanol aqueous solution with a volume fraction of 60%, and carry out reflux extraction at 70 ° C for 3 times, each extraction for 3 hours, to obtain an ethanol extract;

[0074] 2) Concentrating the ethanol extract obtained in step 1) under a pressure of 0.09 MPa, and filtering to obtain the ethanol concentrate;

[0075] 3) Adsorb the ethanol concentrate obtained in step 2) with the AB-8 type macroporous resin with 7 times the weight of the ethanol concentrate, and after the adsorption is completed, use a volume fraction of 70% ethanol water to elute, and 70% ethanol water and The weight ratio of ethanol concentrated solution is 12:1, obtains ethanol eluate;

[0076] 4) Concentrating the ethanol eluent obtained in step 3) under a pressure of 0.09 MPa to obtain the wild chrysanthemum extract, the specific gravity of the wild chrysanthemum extract is 1.1; the tota...

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Abstract

The invention provides chrysanthemate, a chrysanthemate toothpaste containing the chrysanthemate, and a preparation method of the chrysanthemate toothpaste. The chrysanthemate comprises a flos chrysanthemi indici extract and sodium chloride. The chrysanthemate toothpaste comprises the chrysanthemate, a friction agent, a wetting agent, an adhesion agent, a foaming agent, a sweetening agent, a corrosion remover, an essence, an accessory ingredient and deionized water. According to the chrysanthemate, the chrysanthemate toothpaste containing the chrysanthemate, and the preparation method of the chrysanthemate toothpaste provided by the invention, the flos chrysanthemi indici extract and the sodium chloride are prepared into the chrysanthemate so as to be acted on the toothpaste at the same time, so that a co-synergistic effect is achieved, and oral cavity gingival inflammation can be effectively inhibited and alleviated.

Description

technical field [0001] The invention belongs to the field of oral health care, and in particular relates to chrysanthemum salt, chrysanthemum salt toothpaste containing chrysanthemum salt and a preparation method of chrysanthemum salt toothpaste. Background technique [0002] Toothpaste is a necessary oral cleaning article in people's daily life, and its basic function is to clean teeth and freshen breath. With the advancement of science and technology, people have put forward higher requirements for the ingredients and efficacy of toothpaste. From the clinical data, the safety of table salt is very reliable when used in the oral cavity. Salt (sodium chloride) toothpaste has a strong inhibitory effect on harmful bacteria in the oral cavity, can absorb the tissue fluid of periodontitis, and improve periodontal blood circulation, thus having a certain effect on symptoms such as periodontitis, gingival swelling, and tooth sensitivity. It also has the functions of inhibiting d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/20A61Q11/00
CPCA61K8/20A61K8/97A61Q11/00
Inventor 许海燕何威肖小红夏美莲李超骆朋
Owner 江西草珊瑚口腔护理用品有限公司
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