Preparation method of intelligent pharmaceutical packaging composite membrane

A production process and composite film technology, applied in the direction of synthetic resin layered products, layered products, chemical instruments and methods, etc., can solve the problems of failing to meet GMP requirements, low hygiene and safety standards, poor transparency, etc., and achieve excellent intelligent performance , cost-effective, and the effect of saving production costs

Inactive Publication Date: 2014-06-04
南昌雅太药用包装有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The existing pharmaceutical packaging composite films mainly have the following problems: 1. Low hygienic and safety standards, unable to meet GMP requirements; 2. Poor transparency; 3. A large amount of "three wastes" will be generated during the production process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] Referring to Fig. 1, the present specific embodiment adopts the following technical scheme: it adopts chemical modification and coupling coordination method to synthesize the spiropyran ring with hydroxyl and the spirooxazine pyrrole ring compound through esterification reaction. Ring and spirooxazine pyrrole ring photochromic compound, and then compound the color compound into PET and PE matrix by melt blending and solution casting method to make photochromic PET and PE materials; after that, the traditional pharmaceutical PET / On the basis of the transformation of the AL / PE composite film production line, by adjusting the processes of melt extrusion, biaxial stretching, coating, drying, and winding, it is bonded and laminated with high-barrier AL foil to obtain an intelligent pharmaceutical packaging composite film that combines various performance indicators .

[0008] Compared with the traditional PET / AL / PE composite film material, this specific implementation mode ...

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Abstract

The invention discloses a preparation method of an intelligent pharmaceutical packaging composite membrane, and belongs to the field of pharmaceutical packaging. According to the preparation method, chemical modification and coupling coordination are adopted so as to synthesis a photochromic compound containing spiropyrane rings and spirooxazine pyrrole rings via esterification reaction of hydroxyl-containing spiropyrane rings with a spirooxazine pyrrole ring compound; combination of the photochromic compound with PET and PE matrix in realized via melt blending and solution casting so as to obtain photochromic PET and PE materials; and then the intelligent pharmaceutical packaging composite membrane with qualified performance indexes is obtained based on modification of traditional pharmaceutical PET/AL/PE composite membrane production line, via adjusting melt extrusion, two-way stretch, coating, drying, and rolling technology, and via bonding combination with high-barrier aluminum foil.

Description

[0001] Technical field: [0002] The invention relates to a pharmaceutical packaging composite film, in particular to a production process of an intelligent pharmaceutical packaging composite film. Background technique: [0003] The existing pharmaceutical packaging composite films mainly have the following problems: 1. Low hygienic and safety standards, unable to meet GMP requirements; 2. Poor transparency; 3. A large amount of "three wastes" will be generated during the production process. Invention content: [0004] The purpose of the present invention is to provide a production process of intelligent pharmaceutical packaging composite film. Compared with the traditional PET / AL / PE composite film material, it has excellent environment-sensitive discoloration function, high cost performance, and excellent intelligent performance. The production process only needs On the basis of the original equipment, proper process parameter adjustment can realize continuous production...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B32B15/09B32B27/08
Inventor 郑国高
Owner 南昌雅太药用包装有限公司
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