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Model building method and device for protein interaction

A model building and protein technology, applied in the field of biology, can solve problems such as the inability to predict the correlation between protein interactions and diseases, and achieve the effect of predicting the correlation between protein interactions and diseases

Inactive Publication Date: 2016-06-29
NAT UNIV OF DEFENSE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The main purpose of the present invention is to provide a protein interaction model building method and device to solve the problem that the prior art cannot predict the correlation between protein interaction and disease

Method used

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  • Model building method and device for protein interaction
  • Model building method and device for protein interaction
  • Model building method and device for protein interaction

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Embodiment Construction

[0029] It should be noted that, in the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and examples.

[0030] In order to enable those skilled in the art to better understand the solutions of the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only It is an embodiment of a part of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0031] It should be noted that the terms "fir...

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Abstract

The invention discloses a protein interaction model building method and device. The protein interaction model building method includes: obtaining classification features of protein interactions; obtaining protein interaction prediction models according to the classification features; and detecting disease-related protein interactions according to the prediction models. Through the present invention, the correlation between protein interaction and disease can be predicted.

Description

technical field [0001] The invention relates to the field of biology, in particular to a method and device for establishing a protein interaction model. Background technique [0002] Disease-associated genes are a group of genes closely related to disease states. They play an important role in the occurrence, development, treatment and prognosis of diseases, and are often used in the discovery of biomarkers and drug targets. However, since most proteins exert biological functions by interacting with other proteins, it is not only necessary to examine the impact of a single protein on the disease, but also to examine the role of protein interactions on the occurrence and development of diseases, so as to help understand the pathogenesis. disease mechanism. [0003] At present, there are some methods to predict the druggability of protein interactions (that is, a protein can be combined with small molecule drugs as the target of drug action), and experimental methods are used...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06F17/50G06F19/12
Inventor 刘伟谢红卫
Owner NAT UNIV OF DEFENSE TECH
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