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Oral preparation for treating cerebral apoplexy and preparation method and application thereof

A stroke and drug technology, which is applied in the oral preparation of Xingnaojing and its preparation, and in the field of medication for the recovery of neurological deficits in the recovery period of stroke, can solve the problems of high price of Xingnao injection, unsuitable for long-term medication, etc., and achieve remarkable results. Effect

Inactive Publication Date: 2011-05-04
JIANGXI JEMINCARE GRP CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned extract and volatile oil jointly form Xingnaojing pharmaceutical composition (hereinafter referred to as Xingnaojing pharmaceutical composition for this pharmaceutical composition), supplemented with pharmaceutically acceptable excipients, processed into oral preparations, and used for cerebral palsy. Recovery treatment after stroke overcomes the disadvantages of high price of Xingnao Injection and unsuitable for long-term medication

Method used

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  • Oral preparation for treating cerebral apoplexy and preparation method and application thereof
  • Oral preparation for treating cerebral apoplexy and preparation method and application thereof
  • Oral preparation for treating cerebral apoplexy and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Preparation of Oral Solution

[0091]Prescription: 7.5 parts of artificial musk, 30 parts of turmeric, 30 parts of gardenia, 1 part of borneol

[0092] Take the above-mentioned four medicinal materials in parts by weight, add artificial musk into a supercritical fluid extraction kettle, extract 3 hours at an extraction pressure of 30 MPa, and a temperature of 40 ° C, and analyze to obtain artificial musk volatile oil; take gardenia and turmeric medicinal material particles, add to In the supercritical fluid extraction kettle, the extraction pressure is controlled at 40MPa, the temperature is 35°C, and the extraction is carried out for 4 hours to obtain gardenia volatile oil and turmeric volatile oil.

[0093] Take the gardenia and turmeric medicinal materials after extracting the volatile oil, heat and extract with 60% ethanol for 3 times, each time for 1.5 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and make the weight ratio of the...

Embodiment 2

[0096] Tablet preparation

[0097] Prescription: 3 parts of artificial musk, 16 parts of turmeric, 16 parts of gardenia, 0.1 part of borneol

[0098] Take the above-mentioned four medicinal materials in parts by weight, add artificial musk into a supercritical fluid extraction kettle, extract at 40 MPa at an extraction pressure of 50° C., extract for 4 hours, analyze, and obtain artificial musk volatile oil; take gardenia and turmeric medicinal material particles, add In the supercritical fluid extraction kettle, the extraction pressure is controlled at 30MPa, the temperature is 40°C, and the extraction is performed for 3 hours to obtain gardenia volatile oil and turmeric volatile oil.

[0099] Take the gardenia and turmeric medicinal materials after extracting the volatile oil, heat and extract with 30% ethanol for 3 times, each time for 1.5 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and make the weight ratio of the medicinal liquid to t...

Embodiment 3

[0102] Preparation of granules

[0103] Prescription: 1 part of artificial musk, 10 parts of turmeric, 10 parts of gardenia, 0.1 part of borneol

[0104] Take the above four medicinal materials in parts by weight, add artificial musk into a supercritical fluid extraction kettle, extract for 3 hours at an extraction pressure of 40 MPa, and a temperature of 40° C., and analyze to obtain artificial musk volatile oil; take gardenia and turmeric medicinal material particles, add to In the supercritical fluid extraction kettle, the extraction pressure is controlled at 30MPa, the temperature is 40°C, and the extraction is performed for 2 hours to obtain gardenia volatile oil and turmeric volatile oil.

[0105] Take the gardenia and turmeric medicinal materials after extracting the volatile oil, heat and extract them with 70% ethanol for 3 times, each time for 2 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and make the weight ratio of the medicinal...

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Abstract

The invention discloses a medicinal composition for treating medium convalescent nerve function defect of cerebral apoplexy, a preparation method for the medicinal composition and medicinal application of the medicinal composition in preparation of a medicament for medium and posterior nerve function defect of cerebral apoplexy. Natural musk is replaced by adopting artificial musk so as to reduce the application cost and save resources; and the volatile oil is extracted by adopting supercritical fluid technology, effective ingredients are refined and purified by adopting macroporous absorption resin technology, and the effective ingredients are high and have good treatment effect on the medium convalescent cerebral apoplexy, particularly medium and posterior nerve function defect of cerebral apoplexy.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to an oral preparation of Xingnaojing, a preparation method thereof and the use of medicine for recovering neurological function defect in the recovery period of stroke. Background technique [0002] Stroke, commonly known as apoplexy, has become one of the three diseases with the highest human mortality rate. It is also the disease with the fastest development, the slowest recovery, the most death, and the most severe disability among the major diseases. It brings great harm to patients and society. There is serious danger. [0003] Cerebral stroke is a sudden loss of body function due to cerebral vascular disease. It is divided into two categories: ischemic stroke and hemorrhagic stroke. Among them, ischemic stroke is the main one, accounting for about 70% of the total. . According to the different stages of its onset and treatment, stroke is divi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10A61P25/00A61K31/045A61K31/122
Inventor 刘文尧
Owner JIANGXI JEMINCARE GRP CO LTD
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