Clinical condition evaluation new system for predicting one-year joint destruction progress of rheumatoid arthritis patient
An arthritis and rheumatoid technology, applied in the medical field, can solve problems such as joint erosion and damage, large indirect economic losses for patients, and failure to effectively prevent the progress of joint damage in RA patients, so as to avoid disability, reduce or block the progress of joint damage Effect
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Embodiment 1
[0024] The determination of embodiment 1 new index extremity muscle index (ASMI)
[0025]1. Among RA patients who completed the standard treatment according to the guidelines and were followed up for 1 year, the baseline body composition index variables that could predict the progression of radiographic joint destruction in 1 year were screened, and the gender was corrected by univariate and multivariate logistic regression analysis. , age, disease duration, rheumatoid factor (RF) status, anti-cyclic citrullinated peptide antibody (ACPA) status, smoking status, DAS28-CRP, Stanford Health Assessment Questionnaire-Disability Index (HAQ-DI), imaging modified sharp score Baseline ASMI (OR=0.625, 95%CI: 0.423-0.925) and sarcopenia (OR=2.139, 95%CI: 1.221-3.747) were screened out after baseline indicators such as total score (mTSS) and accumulated medication within 1 year They are the predictors of 1-year radiographic joint destruction progression in RA patients, that is, after adju...
Embodiment 2
[0035] Example 2 A new system for evaluating the clinical condition of patients with rheumatoid arthritis for 1 year of joint destruction progress
[0036] A new clinical condition assessment system for predicting the progression of joint destruction in patients with rheumatoid arthritis within one year, including the clinical condition assessment system recommended by the guidelines, and the new indicator ASMI in Example 1.
[0037] According to the new system, the process of evaluating the clinical condition and guiding the treatment of patients with rheumatoid arthritis is shown as follows: figure 1 Shown: On the basis of the clinical condition evaluation system recommended by the guidelines, the baseline body composition analysis was performed on the overall RA patients, and the patients were divided into two groups: baseline sarcopenia and baseline non-sarcopenia, for patients with baseline non-sarcopenia After 3 months of treatment, the muscle changes were monitored, and...
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