An integrated system for photothermal therapy and temperature monitoring with replaceable probes

Abstract

The invention discloses an integrated system for photothermal therapy and temperature monitoring with replaceable probes, comprising a computer, a spectrometer, a laser light source, a coupler, a laser fiber, a temperature measuring fiber, a double-beam fiber, a probe, and a temperature controller; The probe is filled with photothermotherapy composite material, and it has a detachable structure to facilitate the replacement of probes with different filling materials; the laser is coupled with the temperature measuring fiber through the laser fiber through the coupler, and then transmitted to the probe through the double-beam fiber for photothermotherapy. The composite material is excited, and the excited fluorescence is transmitted to the spectrometer through the double-beam fiber and the temperature measuring fiber to read the fluorescence intensity of two different wavelengths. The computer performs real-time calculation through the fluorescence intensity ratio method to obtain the real-time temperature of the probe. The temperature controller is used to control the power of the laser, so as to realize the effect of real-time monitoring and real-time temperature control. The invention is small in size, can be monitored and controlled in real time, has the characteristics of modularization, and can replace the laser light source, the optical fiber and the probe head.

Description

technical field [0001] The invention relates to a photothermal therapy and temperature monitoring integrated system with replaceable probes. Background technique [0002] With the continuous progress of modern medical technology, the application of laser treatment technology is gradually widespread. Laser has the characteristics of good monochromaticity, good coherence, good directionality and high brightness. Good directionality means that the laser has a smaller divergence angle in the transmission process than the daily light source, so the energy can be better concentrated in one place, and the high energy of the laser is used to irradiate the object to make it heat up quickly, and then change the structure. Therefore, laser has become a new method of processing and treatment. The laser is irradiated to the patient site through an optical fiber to increase the temperature of the irradiated biological tissue to kill the diseased cells, which is often used in tumor trea...

AI Technical Summary

Problems solved by technology

However, traditional laser hyperthermia has problems such as delay in temperature monitoring, poor heating effect, large volume of treatment devices, toxicity and easy residue of indirect heat conduction substances, etc.

[0003] When the temperature rises above 45°C, the diseased cells will be gradually killed. If the heating rate of the laser is too fast, there will be a delay in temperature monitoring, which may cause damage to normal body cells, resulting in unnecessary secondary damage

The current real-time monitoring temperature probe is too large to enter some parts of the human body for treatment, and the replacement is complicated and the maintainability is low

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