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Gynecological antibacterial repair gel and preparation method thereof

A gynecological and gel technology, which is applied in the direction of local antibacterial agents, pharmaceutical formulas, medical preparations with non-active ingredients, etc., can solve problems such as lack of repairing effect, achieve shortening repair time, improve gynecological environment, and promote wound repair ability Effect

Pending Publication Date: 2020-02-28
BEIJING BEST LIFE REGENERATIVE MEDICINE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current gynecological gel can be used to treat various gynecological vaginitis and cervicitis, including bacterial vaginosis, fungal vaginitis, etc., and has good antibacterial effect, but it lacks sufficient repairing effect on vaginal erosive tissue wounds

Method used

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  • Gynecological antibacterial repair gel and preparation method thereof
  • Gynecological antibacterial repair gel and preparation method thereof
  • Gynecological antibacterial repair gel and preparation method thereof

Examples

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preparation example Construction

[0056] A preparation method of gynecological antibacterial repairing gel, (1) weighing the raw materials of each component according to the formula, and setting aside;

[0057] (1) take each component according to above-mentioned raw material and percentage thereof, standby;

[0058] (2) Disperse the gel agent in 2 / 3 dispersant, stir evenly, obtain the pre-dispersed gel agent, set aside;

[0059] (3) Dissolve the antibacterial agent and care-type ingredients in water, and after fully stirring, add to the pre-dispersed gel, and fully stir to form a gel to obtain the first mixture;

[0060] (4) Disperse the bioactive silicon and the tactile agent in the remaining 1 / 3 dispersant, and then add the first mixture described in step (3) to obtain the second mixture;

[0061] (5) Add an appropriate amount of pH adjuster to the second mixture to adjust the pH to 3.5-7.5, and after standing to defoam, the gynecological antibacterial repair gel is obtained.

Embodiment 1

[0063] Take raw materials according to the following quality formula: 0.3% of chlorhexidine acetate, 2.5% of hydroxypropyl methylcellulose, 6% of glycerol, 0.5% of bioactive silicon (Regesi produced by commercially available Beijing Xingfu Yisheng High-tech Co., Ltd. Regenerated silicon V type), 6% of nursing ingredients, 0.1% of citric acid, 0.1% of borneol, and the balance is water. Among them, based on the total amount of gel raw materials, the nursing ingredients are specifically composed of the following ingredients: Ginkgo biloba extract 1%, ginseng extract 0.2%, motherwort extract 0.5%, aloe vera extract 2%, Centella asiatica extract 0.5%, Arbutin 0.5%, Licorice Extract 0.3%, Cactus Extract 1%.

[0064] Firstly, hydroxypropyl methylcellulose is dispersed in 2 / 3 of glycerol to obtain a pre-dispersed gel, which is ready for use. Then, the antibacterial agent chlorhexidine acetate and the nursing ingredients are dissolved in the water of the formulation amount, stirred an...

Embodiment 2

[0066] Take raw materials according to the following quality formula: 0.3% of chlorhexidine acetate, 3% of hydroxyethyl cellulose, 9% of glycerol, 2% of bioactive silicon (Regesi regenerated silicon produced by commercially available Beijing Xingfu Yisheng High-tech Co., Ltd. Type V), 6% of nursing ingredients, 0.4% of citric acid, 0.1% of borneol, and the balance is water. Among them, the nursing ingredients are composed of the following ingredients: Ginkgo biloba extract 1%, ginseng extract 0.2%, motherwort extract 0.5%, aloe vera extract 2%, centella asiatica extract 0.5%, arbutin 0.5%, licorice extract Extract 0.3%, cactus extract 1%.

[0067] Firstly, hydroxyethyl cellulose is dispersed in 2 / 3 of glycerol to obtain a pre-dispersed gel, which is ready for use. Then, the antibacterial agent chlorhexidine acetate and the nursing ingredients are dissolved in the water of the formulation amount, stirred and dissolved, then added into the pre-dispersed gel, stirred to form a g...

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Abstract

The invention provides gynecological antibacterial repair gel and a preparation method thereof; the gynecological antibacterial repair gel is prepared from, by weight, 1-10% of gel, 0.01-6% of an antibacterial agent, 0.1-6% of bioactive silicon, 2-20% of nursing components, 0.1-15% of a dispersant, 0.1-1% of a pH adjuster, and the balance of water; the gynecological antibacterial repair gel has excellent antibacterial property, good biocompatibility and good anti-inflammation and antipruritic effects, has a certain wound repairing effect, and can be used for treating gynecological diseases, such as vaginitis and cervicitis.

Description

technical field [0001] The invention relates to a gynecological antibacterial repair gel and a preparation method thereof, in particular to a gynecological antibacterial repair gel comprising a gel, an antibacterial agent, a nursing component, a bioactive silicon, a dispersant, a pH regulator, and a tactile agent and its preparation method. Background technique [0002] Gynecological diseases are common diseases among women. Unbalanced flora, damaged mucous membranes, and microenvironmental damage can all lead to the occurrence of gynecological diseases, such as trichomonal vaginitis and bacterial vaginosis, which bring great harm to women's life and work. Impact. According to statistics, the incidence rate of various gynecological diseases is as high as 65%. [0003] The treatment of such gynecological diseases, in addition to relying on autoimmunity, is usually accompanied by drug treatment, but the onset of this type of infection is mostly on the mucosal surface, so ext...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K47/38A61K47/36A61K45/06A61K36/896A61K36/886A61P15/02A61P15/00A61P31/02A61K33/00A61K31/155A61K31/7034
CPCA61K9/0034A61K9/06A61K31/155A61K31/7034A61K33/00A61K36/16A61K36/23A61K36/258A61K36/33A61K36/484A61K36/533A61K36/886A61K36/896A61K45/06A61K47/36A61K47/38A61P15/00A61P15/02A61P31/02A61K2300/00
Inventor 胡方刘明东仇越秀
Owner BEIJING BEST LIFE REGENERATIVE MEDICINE TECH CO LTD
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