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A traditional Chinese medicine composition for multi-target inhibition of seborrheic alopecia and preparation method thereof

A technology for seborrheic alopecia and composition, which is applied in the direction of drug combination, pharmaceutical formula, hair care, etc., to achieve the effects of convenient application, simple preparation, and low production cost

Active Publication Date: 2015-08-19
GUANGZHOU TIANWEN JIAOYAN COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine treatment is mainly based on traditional Chinese medicine theory using Chinese herbal medicine for treatment. The existing traditional Chinese medicine treatment is mainly based on the principle of combining disease and syndrome differentiation in the treatment of hair loss in traditional Chinese medicine. By screening natural herbal medicines that nourish blood and calm the nerves, soothe the liver and relieve stagnation, and benefit qi and hair growth However, the currently published Chinese herbal medicine compound or related preparations do not simultaneously target multiple targets such as controlling 5α-reductase activity, AR expression, and microbial infection of the scalp and hair

Method used

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  • A traditional Chinese medicine composition for multi-target inhibition of seborrheic alopecia and preparation method thereof
  • A traditional Chinese medicine composition for multi-target inhibition of seborrheic alopecia and preparation method thereof
  • A traditional Chinese medicine composition for multi-target inhibition of seborrheic alopecia and preparation method thereof

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preparation example Construction

[0031] The preparation method of the Chinese medicine composition of the multi-target inhibition seborrheic alopecia of embodiment 9 to 11 in the table 2 is specifically: Angelica sinensis extract, Sophora flavescens extract, Radix Astragali extract, Scutellaria baicalensis extract, Shegan extract, Han Fangji extract, notopterygium extract, sorrel extract, broad bean root extract, and Sophora japonica extract are mixed according to the dosages of the corresponding examples in Table 2, and the corresponding multi-target traditional Chinese medicine composition for inhibiting seborrheic alopecia can be obtained The preparation steps of each Chinese herbal medicine extract are as follows: pulverize the corresponding Chinese herbal medicine, soak the pulverized Chinese herbal medicine in pure water for 15 days under normal pressure, and the soaking extraction temperature is 35°C; filter the mixed solution obtained after soaking, and prepare the obtained The filtrate was concentrate...

Embodiment 23

[0042] The preparation steps of each Chinese herbal medicine extract in Example 23 and Example 24 include: pulverizing the corresponding Chinese herbal medicine, soaking the pulverized Chinese herbal medicine in 70% (mass percentage) ethanol under negative pressure for 7 days, and the soaking extraction temperature is 20 °C; filter the mixed solution obtained after soaking, and concentrate the obtained filtrate at 40 °C to obtain the corresponding Chinese herbal medicine extract.

Embodiment 25

[0043] The preparation steps of each Chinese herbal medicine extract in Example 25 and Example 27 are as follows: pulverize the corresponding Chinese herbal medicine, soak the pulverized Chinese herbal medicine in pure water under normal pressure for 15 days, and the soaking extraction temperature is 35° C.; filter and soak to obtain Concentrate the obtained filtrate at 60°C to obtain the corresponding Chinese herbal medicine extract.

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Abstract

The invention relates to a medicine compound for preventing alopecia, in particular to a multiple-target-point traditional Chinese medicine compound for restraining the seborrhoeic alopecia. The traditional Chinese medicine compound is prepared from angelica extract, shrubby sophora extract, astragalus extract, scutellaria baicalensis extract, blackberry lily extract, stephania terandra extract, notopterygium root extract, garden sorrel extract, subprostrate sophora root extract and sophora fruit extract. Each type of extract accounts for 0.1-99.1% of the traditional Chinese medicine compound in weight. The traditional Chinese medicine compound can control the multiple target points of 5 alpha-reductase activity, AR expression, scalp hair microbial infection and the like at the same time and treat the seborrhoeic alopecia effectively, and is low in stimulation on the human body and low in toxicity.

Description

technical field [0001] The invention relates to a pharmaceutical composition for preventing hair loss, in particular to a traditional Chinese medicine composition for multi-target inhibition of seborrheic alopecia; the present invention also relates to a preparation method of the multi-target anti-seborrheic alopecia Chinese medicine composition . Background technique [0002] Seborrheic alopecia (SA) used to be called premature baldness, male pattern baldness, male baldness, diffuse alopecia, common alopecia, etc. Its disease is related to heredity, androgen, seborrhea, and bacterial infection. "Tinea" or "moth-eaten hair loss", due to the invasion of the skin by damp heat, the nutrition is imbalanced, the interstitial texture is not solid, the veins are stagnant, and the biochemistry of essence and blood is unfavorable, so that the hair root is not solid and causes hair loss. Although hair loss does not cause physical pain, it does a great deal of damage to appearance, da...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61K8/97A61P17/08A61P17/14A61Q5/02A61Q5/12
Inventor 吴培诚欧春凤梁高卫邹宏图刘伟成姚中华周磊
Owner GUANGZHOU TIANWEN JIAOYAN COSMETICS
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