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Medicinal preparation for treating migraine and preparation method thereof

A pharmaceutical preparation and migraine technology, applied in the field of traditional Chinese medicine, can solve problems such as adverse reactions, difficult to cure completely, and no specific treatment methods

Inactive Publication Date: 2012-07-11
SOUTHWEST JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, it is still difficult to be completely cured, and there is no specific treatment so far
Western medicine is often used for acute migraine attacks, such as non-steroidal anti-inflammatory drugs, ergotamines, and triptans, but there are usually adverse reactions, so it is not suitable for long-term use

Method used

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  • Medicinal preparation for treating migraine and preparation method thereof
  • Medicinal preparation for treating migraine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A specific embodiment of the present invention is a pharmaceutical preparation for treating migraine, which includes the following drug raw materials: 20g Rhizoma Chuanxiong, 15g Angelica dahurica, 15g Notopterygium, 10g Tianma, 15g Tiannanxing, 20g Vinegar Corydalis, Ben 15g, Astragalus 30g, Angelica 15g.

[0036] The method for preparing the described pharmaceutical preparation for the treatment of migraine, its specific steps are as follows:

[0037] A, get the vinegar Corydalis Corydalis of described proportion, extract 3 times with ethanol aqueous solution, the mass fraction of the ethanol aqueous solution used each time is 80%, the volume is 6 times of vinegar Corydalis Corydalis, each extraction time is 2 hours; filter after extraction , combined the filtrates, recovered ethanol, concentrated to obtain a clear paste with a relative density of 1.10 at 60°C, and set aside;

[0038] B. Take the Rhizoma Chuanxiong, Angelica dahurica, Notopterygium, Angelica, and Ligus...

Embodiment 2

[0042] A specific embodiment of the present invention is a pharmaceutical preparation for treating migraine, which includes the following pharmaceutical raw materials: 10g of Rhizoma Chuanxiong, 10g of Angelica dahurica, 10g of notopterygium, 5g of Gastrodia elata, 10g of Tiannanxing, 10g of vinegar Corydalis, Ben 10g, Astragalus 20g, Angelica 10g;

[0043] The method for preparing the described pharmaceutical preparation for the treatment of migraine, its specific steps are as follows:

[0044] A, get the vinegar Corydalis Corydalis of described proportion, extract 2 times with ethanol aqueous solution, the mass fraction of the ethanol aqueous solution used each time is 70%, volume is 3 times of vinegar Corydalis Corydalis, each extraction time is 1 hour; filter after extraction , combine the filtrates, reclaim ethanol, concentrate to obtain a clear paste, and set aside;

[0045] B. Take the Rhizoma Chuanxiong, Angelica dahurica, Notopterygium, Angelica, and Ligusticum eduli...

Embodiment 3

[0049] A specific embodiment of the present invention is a pharmaceutical preparation for treating migraine, which includes the following pharmaceutical raw materials: 30g Rhizoma Chuanxiong, 25g Angelica dahurica, 25g notopterygium, 15g Gastrodia elata, 25g Zhitiananxing, 30g vinegar Corydalis, Ben 25g, Astragalus 50g, Angelica 25g.

[0050] The method for preparing the described pharmaceutical preparation for the treatment of migraine, its specific steps are as follows:

[0051] A, get the vinegar Corydalis Corydalis of described proportion, extract 4 times with ethanol aqueous solution, the mass fraction of the ethanol aqueous solution used each time is 90%, the volume is 8 times of vinegar Corydalis Corydalis, each extraction time is 3 hours; filter after extraction , combine the filtrates, reclaim ethanol, concentrate to obtain a clear paste, and set aside;

[0052] B. Take the Rhizoma Chuanxiong, Angelica dahurica, Notopterygium, Angelica, and Ligusticum edulis in the d...

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Abstract

The invention discloses a medicinal preparation for treating migraine and a preparation method thereof. The medicinal preparation comprises the following raw medicines according to the proportion: 10-30 grams of Ligusticum chuanxiong, 10-25 grams of angelica root, 10-25 grams of notopterygium root, 5-15 grams of gastrodia elata, 10-25 grams of prepared rhizoma arisaematis, 10-30 grams of Rhizoma Corydalis processed with vinegar, 10-25 grams of ligusticum, 20-50 grams of Astragalus root and 10-25 grams of Angelica sinensis. The preparation method of the treating migraine comprises the following steps of: utilizing ethanol to extract the Rhizoma Corydalis processed with the vinegar to obtain a concentrated extract; distilling by water vapor and extracting volatile oil; adding water into a mixture of dregs of a decoction, the gastrodia elata, the prepared rhizoma arisaematis and the Astragalus root and boiling; combining the solution with the aqueous solution; filtering and concentrating a filtering solution to obtain an extract; combining the extract with the concentrated extract of the Rhizoma Corydalis processed with the vinegar and concentrating the mixture to obtain a thick extract; and spraying the volatile oil to prepare various preparations. The medicinal preparation disclosed by the invention can better keep effective components in the medicine and has a good treating effect; aiming at the prior art, a traditional Chinese medicine formula is prepared into a modern preparation by the preparation method, so that the medicinal preparation disclosed by the invention is convenient to orally take and the process is scientific and reasonable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy. technical background [0002] Migraine is a recurrent throbbing headache, which belongs to the "big family" among many types of headaches. Before the attack, there are often auras such as flashes of light, blurred vision, and numbness of limbs, which may be accompanied by neurological and mental dysfunction. It is a progressive disease, usually with increasing frequency. Migraine is one of the most common clinical symptoms. Its pathogenesis is very complicated. It is characterized by recurrent unilateral throbbing headache. The prevalence rate of the population is 5-40%, and the incidence rate varies greatly. 2-3 times that of men. The disease has a long course of disease, intermittent and repeated attacks, and is lingering and difficult to heal, which seriously affects the patient's work, study and quality of life. The exact etiology and pathogenesis of migraine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/06
Inventor 万军周霞刘睿颖
Owner SOUTHWEST JIAOTONG UNIV
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