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Intra-arterial heating infusion set and method

An infusion device and internal heating technology, applied in the field of infusion, can solve the problems of patients with large trauma, complicated blood vessel treatment operations, and susceptibility to infection, and achieve the effects of fast heating speed, reduced treatment costs, and simple process

Active Publication Date: 2008-11-26
TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The purpose of the present invention is to overcome the defects that the existing whole-body hyperthermia method and related devices need whole-body anticoagulation in clinical application, the blood vessel treatment operation is complicated, the trauma to the patient is large, and it is easy to infect, thereby providing a kind of blood vessel injection hyperthermia Physiological saline or hydrated exothermic substance, so as to rapidly increase the blood temperature and then transfer the heat to the temperature of adjacent parts and distal tissues by means of blood flow, and an infusion-type intravascular heating device and method

Method used

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  • Intra-arterial heating infusion set and method

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Effect test

Embodiment 1

[0036] One way to heat the body temperature is to directly inject high-temperature physiological saline into the blood circulation system of the human body, and transport the heat of the high-temperature saline to all parts of the body with the help of blood circulation, so as to heat the body and kill tumors purpose of cells. As we all know, the specific heat of normal saline is as high as 4200J / kg·℃. After the tiny droplets of normal saline full of heat enter the blood, they quickly lower their own temperature and release heat to the surrounding blood. Because the heat exchange process is very fast and can be completed in less than 100ms, it will not cause damage to the cells and can increase the temperature of the blood.

[0037] The purpose of whole-body hyperthermia is to raise the temperature of the body evenly and reach above 42°C. Human tissue is a water-rich material, with a normal water content of over 60%. The rise in body temperature is essentially the process of...

Embodiment 2

[0054] Another way to achieve body temperature heating is the hydration exothermic method, in which a hydratable exothermic compound whose reaction product is harmless and absorbable is injected directly into the bloodstream in a drip. The compound and the water in the blood plasma have an exothermic reaction at the atomic level, and a very small amount of reactant can obtain huge heat energy. With the gradual progress of the dripping process, the heat energy source is continuously delivered to all parts of the body. As we all know, realizing intravascular drug administration by way of drip has become one of the most conventional medical methods in medical treatment at present, and its implementation process is safe, convenient, fast and easy to be accepted by patients. Realizing whole-body hyperthermia by infusion is a new concept of whole-body hyperthermia for tumors that is different from the past.

[0055] The heat release of hydration is actually a process of heat absorp...

Embodiment 3

[0062] Another method for heating the body temperature is to directly utilize the exothermic heat of the acid-base neutralization reaction to increase the blood temperature. As we all know, acid-base neutralization reaction releases a lot of heat. However, this method is difficult to be accepted by clinicians and patients because of the strong corrosiveness of acids and alkalis. In fact, if a more reasonable method is adopted, the rational utilization of this part of energy can be realized. In the present invention, the acid and alkali are transported in their respective micro channels, and before entering the blood, tiny alkali droplets and acid droplets are mixed, and the mixed solution is ejected into the blood at an extremely fast speed in an extremely small moment , Complete the chemical reaction and exothermic reaction in the blood.

[0063] Take the common acid HCl and common NaOH as an example. During the acid-base neutralization reaction, the reaction heat of HCl an...

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Abstract

The invention discloses an intravessel heating infusion device, comprising a transfusion bottle, a transmission pipe and a puncture needle; wherein, an electric heater is arranged in or on the puncture needle, and the electric heater is connected with a power supply and used for heating liquid which flows in the puncture needle. The intravessel heating infusion device does not need complicated medical equipment during the implementation process, only an ordinary drop device and a corresponding temperature monitoring device are needed for the infusion, the process is simple and convenient, a patient can be directly treated at an out-patient department without the need of being in a hospital; when in whole body hyperthermia, the speed of the temperature increase of the machine body is rapid. Blood circulation can transmit the heat to the whole body within dozens of minutes.

Description

technical field [0001] The invention relates to an infusion device, in particular to an infusion device for intravascular heating, and also relates to an infusion method. Background technique [0002] Tumor hyperthermia is a physical therapy method that uses artificially raising the temperature of the human body to achieve the elimination of tumors. It can generally be divided into two categories: local heating and whole-body heating. At present, local heating therapy is more popular, and the corresponding equipment includes ultrasound, radio frequency, microwave, laser and so on. However, for the clinically more common malignant tumors that have spread throughout the body, local hyperthermia is difficult to be effective. Therefore, the whole body hyperthermia with little side effects is attracting great attention from the clinical medical circle. Whole body hyperthermia can overcome the shortcomings of local hyperthermia in principle because it is aimed at the heating of ...

Claims

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Application Information

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IPC IPC(8): A61M5/14A61M5/44
Inventor 刘静项士海
Owner TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI
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