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Applicaiton of meclofenoxate hydrochloride in preparing medicine for treating femoral head necrosis

A kind of technology of meclofen axetil hydrochloride and femoral head necrosis, which is applied in the field of medicine

Active Publication Date: 2009-07-22
珠海晨安医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no report that meclofenoxate hydrochloride has a medical effect on femoral head necrosis

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] The present invention further illustrates the effect of the present invention through the following experimental data.

[0008] 1. Experimental materials:

[0009] 1.1 Animals

[0010] Experimental animals: adult Japanese white rabbits, 2.1-3.0 kg, provided by the Experimental Animal Center of Hunan Provincial Drug Control Institute, certificate number SYXK (Xiang) 2003-0006.

[0011] 1.2 Drugs and reagents

[0012] Meclofenoxate hydrochloride for injection: (Sino-US joint venture) Shanxi Pude Pharmaceutical Co., Ltd., specification: 0.25g / bottle; batch number: 030901; dilute with water for injection before use.

[0013] Prednisolone acetate: produced by Hubei Pharmaceutical Factory, specification: 125mg / 5ml, batch number: 20040918.

[0014] Penicillin sodium for injection Southwest Pharmaceutical Co., Ltd., specification: 800,000 U, batch number: 20040309 Dilute with water for injection before use.

[0015] 2. Experimental methods and data

[0016] 2.1 Animal grou...

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PUM

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Abstract

The invention relates to the medical use of meclofenoxate hydrochloride. The present invention has good curative effect in treating femoral head necrosis with meclofenoxate hydrochloride. The medicine of the present invention (such as meclofenoxate hydrochloride for injection) can be given by intramuscular injection, intravenous injection or intravenous drip, and can also be given orally by oral preparations (such as meclofenoxate hydrochloride capsules, etc.). Its dosage can generally be administered according to the conventional dosage of meclofenoxate hydrochloride for injection in the prior art. Recommended usage and dosage of the present invention: intravenous injection or intravenous drip, 2-3 times a day, 0.06-0.25g each time; intramuscular injection, 0.06-0.25 once, once every 2 hours.

Description

technical field [0001] The invention relates to the medical use of meclofenoxate hydrochloride, that is, the application of meclofenoxate hydrochloride in the preparation of medicines for treating femoral head necrosis, and belongs to the technical field of medicine. Background technique [0002] Femoral head necrosis is a pathological process in which the death of living components of bone (bone cells, bone marrow hematopoietic cells and fat cells) is the main change. Necrosis of the femoral head is a chronic disease in the world. Due to its complicated etiology, difficult treatment, and high disability rate if it is not treated in time, it seriously endangers the life and work of patients. Therefore, it is called "undead cancer", which shows how harmful it is. Osteonecrosis is most common with femoral head necrosis. According to reports, there are between 150,000 and 200,000 new cases of femoral head necrosis in my country every year, and the cumulative number of cases re...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/221A61P19/08
Inventor 刘遵路李润宝余辉陈雪红杨旸
Owner 珠海晨安医药有限公司
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